The Fresh Beat Band is a children's TV show with original pop songs produced for Nick Jr. The Fresh Beats are Shout, Twist, Marina, and Kiki, described as four best friends in a band who go to music school together and love to sing and dance. The show was filmed at Paramount Studios in Los Angeles, California. All episodes follow the same basic structure: ⁕Each episode begins with a song that foreshadows a problem that the band will solve. ⁕The band works together to solve the problem. ⁕When the problem is solved they perform a song with the problem and solution incorporated into the lyrics. ⁕Each episode concludes with a version of The Fresh Beat Band's closing song, "Great Day". ⁕The main characters dance to choreography by Mandy Moore; Sean Cheesman; Chuck Maldonado; Scotty Nguyen; Dreya Weber; Mary Ann Kellogg; Nakul Mahajan; Mihran Kirakosian; Susan Austin and Fred Tallaksen.

A group of musical spies (Twist, Kiki, Shout and Marina) solve mysteries and stop evildoers with the help of Commissioner Goldstar, their monkey sidekick Bo, and gadget guy Reed.